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The Facts about Hormone Replacement For Men

Several of my older male patients have expressed the desire to try natural hormone replacement for men (testosterone). Perhaps you have been considering the same. Like my patients, you may have tried the more natural, gradual methods of boosting testosterone levels by diet, exercise, stress reduction, and avoidance of environmental, or, xenoestrogens.

What’s Available For Clinical Male Replacement Therapy?

If you’re ready to try testosterone replacement via injection or another doctor-prescribed method, here are your options:

Oral route (pills or cheek placement):

Most pills are not that effective and not prescribed within the United States as they can be toxic to the liver. The only pill form that is an exception to this is the testosterone undecanoate form which is absorbed by the lymphatic system, rather than the liver, but must be taken 4 times a day. However, it too is not available in the United States at this time.


The most commonly prescribed form of male HRT. These include cypionate and Sostenon 250, et al. Usually given every 2-3 weeks, it can also be done by self-injection though you might not want to. Side effects can include pain andbleedat the site of injection, bursts of testosterone out of normal range right after injection and low levels right before a scheduled injection

. It is felt that 200 mg every 2 weeks is a good dosage to avoid the highs and lows of testosterone levels with injections. Costs are about $30 a month.


These include AndroGel, AndroDerm, Axiron and are gel/liquid forms that are rubbed into the skin usually at bedtime. The biggest drawback of these is that of transference of hormone to another person if the gel has not completely been absorbed out of the skin before close contact with another person. Must be kept away from children and pregnant women. Axiron is applied under the arms and may help avoid the transference issue.


Testosterone delivered daily via the skin through patches. Thought to without the side effects of injectable testosterone. Side effects can include reaction dermatitis to the patch itself. Also, they are costly – (up to $200 a month).

Male Hormone Replacement

The Pros:

Recent studies have shown that men who have low testosterone can benefit from replacement of testosterone as it can reduce their risks of heart disease and diabetes

  • Andropause symptoms can include weight gain – especially belly fat, high “bad” LDL cholesterol, high blood pressure, insomnia, irritability, depression, low sex drive, memory problems, to name a few.
  • In the above studies, men of ages under 57 to over 63 were treated with testosterone replacement by long-acting injection every 3 months. The results were that they fared very well.

There you have the basics of natural hormone replacement for men that can be prescribed by your doctor. As my patients know, I always recommend that they try the natural methods of boosting testosterone levels for a good amount of time and see how they feel. However, if you are like those patients who feel that their symptoms are not relieved by natural methods, and you wish to try the stronger, clinical route of natural hormone replacement for men, do contact your doctor who can address your specific testosterone issues directly

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